SMARCAL1 - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
SMARCAL1 »  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1   [ EC 3.6.4.- ]
 
Protein also known as:  Sucrose nonfermenting protein 2-like 1.
Gene name:  SMARCAL1
Family name: SNF2/RAD54 helicase » SMARCAL1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 52 1
GENE REF ISO

Function

 show evidences
Overview 
ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA.  
1
  • CuratedUniProtKB
GO molecular function 
Annealing helicase activitydefinition[GO:0036310]  
2
  • IDAUniProtKB
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
DNA bindingdefinition[GO:0003677] silver  
  • IEAInterPro 2 GO
DNA-dependent ATPase activitydefinition[GO:0008094]  
1
  • IMPUniProtKB
Helicase activitydefinition[GO:0004386]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
1
  • IMPGOC
Cellular response to DNA damage stimulusdefinition[GO:0006974]  
1
  • IMPUniProtKB
Chromatin modificationdefinition[GO:0016568] silver  
  • IEAInterPro 2 GO
DNA metabolic processdefinition[GO:0006259]  
1
  • IMPUniProtKB
DNA strand renaturationdefinition[GO:0000733]  
2
  • IDAGOC
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • IMPUniProtKB
Replication fork processingdefinition[GO:0031297]  
1
  • IMPUniProtKB
 

Keywords

Molecular function 
Helicase  definition   [KW-0347]
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SMARCAL1
GenomeRNAi: 50485
PRO: PR:Q9NZC9