IL1RAPL1 - Interleukin-1 receptor accessory protein-like 1 - human protein (Function)
 
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IL1RAPL1 »  Interleukin-1 receptor accessory protein-like 1  (IL1RAPL-1)
 
Protein also known as:  Three immunoglobulin domain-containing IL-1 receptor-related 2 (TIGIRR-2).
Gene name:  IL1RAPL1
Family name: Interleukin-1 receptor
Entry whose protein(s) existence is based on evidence at protein level
extend overview
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GENE REF ISO

Function

 show evidences
Overview 
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons.  
2
  • CuratedUniProtKB
GO molecular function 
Not  Interleukin-1 bindingdefinition[GO:0019966]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
Receptor bindingdefinition[GO:0005102]  
  • ISSOrtholog Curator
Voltage-gated calcium channel activitydefinition[GO:0005245]  
  • ISSOrtholog Curator
GO biological process 
Calcium ion transmembrane transportdefinition[GO:0070588]  
  • ISSOrtholog Curator
Cation transportdefinition[GO:0006812]  
  • ISSOrtholog Curator
Divalent inorganic cation transportdefinition[GO:0072511]  
  • ISSOrtholog Curator
Heterophilic cell-cell adhesiondefinition[GO:0007157]  
  • ISSOrtholog Curator
Ion transmembrane transportdefinition[GO:0034220]  
  • ISSOrtholog Curator
Metal ion transportdefinition[GO:0030001]  
  • ISSOrtholog Curator
Negative regulation of exocytosisdefinition[GO:0045920]  
1
  • IDAUniProtKB
Neuron differentiationdefinition[GO:0030182]  
  • ISSOrtholog Curator
Positive regulation of dendrite morphogenesisdefinition[GO:0050775]  
  • ISSOrtholog Curator
Presynaptic membrane assemblydefinition[GO:0097105]  
  • ISSOrtholog Curator
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • ISSOrtholog Curator
Regulation of neuron projection developmentdefinition[GO:0010975]  
  • ISSOrtholog Curator
Signal transductiondefinition[GO:0007165] silver  
  • IEAInterPro 2 GO
Transmembrane transportdefinition[GO:0055085]  
  • ISSOrtholog Curator
Transportdefinition[GO:0006810]  
  • ISSOrtholog Curator
 

Keywords

Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: IL1RAPL1
GenomeRNAi: 11141
PRO: PR:Q9NZN1