CRIM1 - Cysteine-rich motor neuron 1 protein - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
CRIM1 »  Cysteine-rich motor neuron 1 protein  (CRIM-1)
 
Protein also known as:  Cysteine-rich repeat-containing protein S52. Cleaved into:  Processed cysteine-rich motor neuron 1 protein.
Gene name:  CRIM1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 25 1
GENE REF ISO

Function

 show evidences
Overview 
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.  
2
  • CuratedUniProtKB
GO molecular function 
Insulin-like growth factor bindingdefinition[GO:0005520] silver  
  • IEAInterPro 2 GO
Insulin-like growth factor-activated receptor activitydefinition[GO:0005010]  
1
  • TASPINC
PDZ domain bindingdefinition[GO:0030165]  
1
  • IDAMGI
Serine-type endopeptidase inhibitor activitydefinition[GO:0004867] silver  
  • IEAInterPro 2 GO
GO biological process 
Insulin-like growth factor receptor signaling pathwaydefinition[GO:0048009]  
1
  • TASGOC
Nervous system developmentdefinition[GO:0007399]  
1
  • TASPINC
Regulation of cell growthdefinition[GO:0001558] silver  
  • IEAInterPro 2 GO
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CRIM1
GenomeRNAi: 51232
PRO: PR:Q9NZV1