TOMM7 - Mitochondrial import receptor subunit TOM7 homolog - human protein (Function)
 
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Protein
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References

 
TOMM7 »  Mitochondrial import receptor subunit TOM7 homolog
 
Protein also known as:  Translocase of outer membrane 7 kDa subunit homolog.
Gene name:  TOMM7
Family name: Tom7
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 13 1
GENE REF ISO

Function

 show evidences
Overview 
Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.  
2
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Protein transmembrane transporter activitydefinition[GO:0008320]  
1
  • TASBHF-UCL
GO biological process 
Protein import into mitochondrial matrixdefinition[GO:0030150] silver  
  • IEAInterPro 2 GO
Protein targeting to mitochondriondefinition[GO:0006626]  
1
  • TASBHF-UCL
Pathways 
According to Reactome, this protein belongs to the following pathway:
Mitochondrial protein import  REACT_118595  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 54543
PRO: PR:Q9P0U1