CACNA1I - Voltage-dependent T-type calcium channel subunit alpha-1I - human protein (Function)
 
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CACNA1I »  Voltage-dependent T-type calcium channel subunit alpha-1I
 
Protein also known as:  Voltage-gated calcium channel subunit alpha Cav3.3 (Ca(v)3.3).
Gene name:  CACNA1I
Entry whose protein(s) existence is based on evidence at protein level
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1 30 4
GENE REF ISO

Function

 show evidences
Overview 
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.11.7  
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Voltage-gated calcium channel activitydefinition[GO:0005245] silver  
  • IBARefGenome
GO biological process 
Calcium ion importdefinition[GO:0070509] silver  
  • IBARefGenome
Membrane depolarization during action potentialdefinition[GO:0086010] silver  
  • IBARefGenome
Neuronal action potentialdefinition[GO:0019228] silver  
  • IEAOrtholog Compara
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • IEAUniProtKB KW
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Sleepdefinition[GO:0030431] silver  
  • IEAOrtholog Compara
Not  Sperm motilitydefinition[GO:0030317] silver  
  • IBARefGenome
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Calcium signaling pathway  hsa04020+8911  
MAPK signaling pathway  hsa04010+8911  
According to Reactome, this protein belongs to the following pathway:
NCAM1 interactions  REACT_18312  
 

Keywords

Biological process 
Calcium transport  definition   [KW-0109]
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Molecular function 
Calcium channel  definition   [KW-0107]
Ion channel  definition   [KW-0407]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: CACNA1I
GenomeRNAi: 8911
PRO: PR:Q9P0X4
Chemistry
GuidetoPHARMACOLOGY: 537