VPS54 - Vacuolar protein sorting-associated protein 54 - human protein (Function)
 
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Protein
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References

 
VPS54 »  Vacuolar protein sorting-associated protein 54
 
Protein also known as:  Hepatocellular carcinoma protein 8.
Gene name:  VPS54
Family name: VPS54
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.  
1
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
GO biological process 
Growthdefinition[GO:0040007] silver  
  • IEAOrtholog Compara
Homeostasis of number of cells within a tissuedefinition[GO:0048873] silver  
  • IEAOrtholog Compara
Musculoskeletal movementdefinition[GO:0050881] silver  
  • IEAOrtholog Compara
Neurofilament cytoskeleton organizationdefinition[GO:0060052] silver  
  • IEAOrtholog Compara
Protein transportdefinition[GO:0015031]  
  • IEAUniProtKB KW
Retrograde transport, endosome to Golgidefinition[GO:0042147] silver  
  • IEAInterPro 2 GO
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 51542
PRO: PR:Q9P1Q0