STK39 - STE20/SPS1-related proline-alanine-rich protein kinase - human protein (Function)
 
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STK39 »  STE20/SPS1-related proline-alanine-rich protein kinase   [ EC 2.7.11.1 ]  (Ste-20-related kinase)
 
Protein also known as:  Serine/threonine-protein kinase 39.
Gene name:  STK39
Entry whose protein(s) existence is based on evidence at protein level
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1 73 2
GENE REF ISO

Function

 show evidences
Overview 
May act as a mediator of stress-activated signals.  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
2
  • IPIBHF-UCL
  • IPIIntAct
Protein kinase bindingdefinition[GO:0019901] silver  
  • IEAOrtholog Compara
Protein serine/threonine kinase activitydefinition[GO:0004674]  
1
  • IDABHF-UCL
Receptor signaling protein serine/threonine kinase activitydefinition[GO:0004702]  
1
  • NASUniProtKB
GO biological process 
Cellular hypotonic responsedefinition[GO:0071476]  
1
  • ICBHF-UCL
Intracellular signal transductiondefinition[GO:0035556]  
1
  • IDABHF-UCL
Negative regulation of potassium ion transmembrane transportdefinition[GO:1901380]  
1
  • IDABHF-UCL
Negative regulation of potassium ion transmembrane transporter activitydefinition[GO:1901017]  
1
  • IDABHF-UCL
Negative regulation of rubidium ion transmembrane transporter activitydefinition[GO:2000687]  
1
  • IDABHF-UCL
Negative regulation of rubidium ion transportdefinition[GO:2000681]  
1
  • IDABHF-UCL
Peptidyl-serine phosphorylationdefinition[GO:0018105]  
1
  • IDABHF-UCL
Peptidyl-threonine phosphorylationdefinition[GO:0018107]  
1
  • IDABHF-UCL
Positive regulation of potassium ion transportdefinition[GO:0043268] silver  
  • IEAOrtholog Compara
Protein phosphorylationdefinition[GO:0006468]  
1
  • NASUniProtKB
Regulation of inflammatory responsedefinition[GO:0050727] silver  
  • IEAOrtholog Compara
Response to stressdefinition[GO:0006950]  
1
  • NASUniProtKB
Signal transduction by phosphorylationdefinition[GO:0023014]  
1
  • IDABHF-UCL
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
 
More information is available from:
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: STK39
GenomeRNAi: 27347
PRO: PR:Q9UEW8
Chemistry
GuidetoPHARMACOLOGY: 2224