PISD - Phosphatidylserine decarboxylase proenzyme - human protein (Function)
 
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Protein
Gene
References

 
PISD »  Phosphatidylserine decarboxylase proenzyme   [ EC 4.1.1.65 ]
 
Cleaved into:  Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain.
Gene name:  PISD
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
Phosphatidylserine decarboxylase activitydefinition[GO:0004609]  
  • IEAEC 2 GO
GO biological process 
Phosphatidylethanolamine biosynthetic processdefinition[GO:0006646]  
  • IEAUniPathway
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 4.1.1.65: Phosphatidyl-L-serine phosphatidylethanolamine + CO(2).  
  • CuratedUniProtKB
It requires the following cofactor
Pyruvoyl group (By similarity).  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycerophospholipid metabolism  hsa00564+23761  
Metabolic pathways  hsa01100+23761  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 
More information is available from:
 

Keywords

Biological process 
Lipid biosynthesis  definition   [KW-0444]
Lipid metabolism  definition   [KW-0443]
Phospholipid biosynthesis  definition   [KW-0594]
Phospholipid metabolism  definition   [KW-1208]
Molecular function 
Decarboxylase  definition   [KW-0210]
Lyase  definition   [KW-0456]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PISD_(gene)
GenomeRNAi: 23761
PRO: PR:Q9UG56