SEC63 - Translocation protein SEC63 homolog - human protein (Function)
 
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Protein
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SEC63 »  Translocation protein SEC63 homolog
 
Gene name:  SEC63
Entry whose protein(s) existence is based on evidence at protein level
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1 22 1
GENE REF ISO

Function

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Overview 
Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the general secretory pathway (sec) family  3.A.5.9.1  
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Protein transporter activitydefinition[GO:0008565] silver  
  • IEAInterPro 2 GO
Receptor activitydefinition[GO:0004872]  
1
  • TASPINC
GO biological process 
Liver developmentdefinition[GO:0001889] silver  
  • IEAOrtholog Compara
Multicellular organismal agingdefinition[GO:0010259] silver  
  • IEAOrtholog Compara
Nitrogen compound metabolic processdefinition[GO:0006807] silver  
  • IEAOrtholog Compara
Posttranslational protein targeting to membranedefinition[GO:0006620]  
1
  • IMPMGI
Posttranslational protein targeting to membrane, translocationdefinition[GO:0031204] silver  
  • IEAInterPro 2 GO
Protein targeting to membranedefinition[GO:0006612]  
1
  • TASPINC
Renal system developmentdefinition[GO:0072001] silver  
  • IEAOrtholog Compara
SRP-dependent cotranslational protein targeting to membranedefinition[GO:0006614]  
1
  • IMPMGI
Pathways 
According to KEGG, this protein belongs to the following pathways:
Protein export  hsa03060+11231  
Protein processing in endoplasmic reticulum  hsa04141+11231  
 

Keywords

Biological process 
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Molecular function 
Chaperone  definition   [KW-0143]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SEC63
GenomeRNAi: 11231
PRO: PR:Q9UGP8