CNTNAP2 - Contactin-associated protein-like 2 - human protein (Function)
 
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Protein
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References

 
CNTNAP2 »  Contactin-associated protein-like 2
 
Protein also known as:  Cell recognition molecule Caspr2.
Gene name:  CNTNAP2
Family name: Neurexin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 68 2
GENE REF ISO

Function

 show evidences
Overview 
May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction.  
  • CuratedUniProtKB
GO molecular function 
Enzyme bindingdefinition[GO:0019899]  
1
  • IPIBHF-UCL
GO biological process 
Adult behaviordefinition[GO:0030534]  
1
  • IMPBHF-UCL
Brain developmentdefinition[GO:0007420]  
1
  • TASBHF-UCL
Cell adhesiondefinition[GO:0007155]  
  • IEAUniProtKB KW
Cellular protein localizationdefinition[GO:0034613]  
  • ISSOrtholog Curator
Cerebral cortex developmentdefinition[GO:0021987]  
2
  • IEPBHF-UCL
Clustering of voltage-gated potassium channelsdefinition[GO:0045163]  
  • ISSOrtholog Curator
Learningdefinition[GO:0007612]  
2
  • IMPBHF-UCL
Limbic system developmentdefinition[GO:0021761]  
1
  • IEPBHF-UCL
Neuron projection developmentdefinition[GO:0031175]  
  • ISSOrtholog Curator
Neuron recognitiondefinition[GO:0008038]  
1
  • NASUniProtKB
Protein localization to juxtaparanode region of axondefinition[GO:0071205]  
  • ISSOrtholog Curator
Social behaviordefinition[GO:0035176]  
2
  • IMPBHF-UCL
Striatum developmentdefinition[GO:0021756]  
1
  • IEPBHF-UCL
Superior temporal gyrus developmentdefinition[GO:0071109]  
1
  • IEPBHF-UCL
Thalamus developmentdefinition[GO:0021794]  
1
  • IEPBHF-UCL
Transmission of nerve impulsedefinition[GO:0019226]  
1
  • NASUniProtKB
Vocalization behaviordefinition[GO:0071625]  
2
  • IMPBHF-UCL
Pathways 
According to KEGG, this protein belongs to the following pathway:
Cell adhesion molecules (CAMs)  hsa04514+26047  
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CNTNAP2
GenomeRNAi: 26047
PRO: PR:Q9UHC6