PGAP2 - Post-GPI attachment to proteins factor 2 - human protein (Function)
 
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Protein
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PGAP2 »  Post-GPI attachment to proteins factor 2
 
Gene name:  PGAP2
Family name: PGAP2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the post-gpi attachment protein (p-gap2) family  9.B.131.1.2  
GO molecular function 
Protein transporter activitydefinition[GO:0008565]  
  • ISSOrtholog Curator
GO biological process 
GPI anchor biosynthetic processdefinition[GO:0006506]  
  • ISSOrtholog Curator
Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatordefinition[GO:0042771] silver  
  • IEAOrtholog Compara
Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damagedefinition[GO:1902230] silver  
  • IEAOrtholog Compara
Protein transportdefinition[GO:0015031] silver  
  • IEAOrtholog Compara
Signal transduction in response to DNA damagedefinition[GO:0042770] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
GPI-anchor biosynthesis  definition   [KW-0337]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 27315
PRO: PR:Q9UHJ9