SLC25A13 - Calcium-binding mitochondrial carrier protein Aralar2 - human protein (Function)
 
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Protein
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References

 
SLC25A13 »  Calcium-binding mitochondrial carrier protein Aralar2
 
Protein also known as:  Mitochondrial aspartate glutamate carrier 2.
Gene name:  SLC25A13
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the mitochondrial carrier (mc) family  2.A.29.14.2  
GO molecular function 
Calcium ion bindingdefinition[GO:0005509]  
1
  • IDAUniProtKB
L-aspartate transmembrane transporter activitydefinition[GO:0015183]  
1
  • IDAUniProtKB
L-glutamate transmembrane transporter activitydefinition[GO:0005313]  
1
  • IDAUniProtKB
Transporter activitydefinition[GO:0005215]  
1
  • NASUniProtKB
GO biological process 
Aspartate transportdefinition[GO:0015810]  
1
  • IDAUniProtKB
ATP biosynthetic processdefinition[GO:0006754]  
1
  • IDAUniProtKB
Cellular respirationdefinition[GO:0045333]  
1
  • IDAUniProtKB
L-glutamate transportdefinition[GO:0015813]  
1
  • IDAUniProtKB
Malate-aspartate shuttledefinition[GO:0043490]  
1
  • IDAUniProtKB
Response to calcium iondefinition[GO:0051592]  
1
  • IDAUniProtKB
Transportdefinition[GO:0006810]  
1
  • NASUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Metabolism  REACT_111217  
Metabolism of proteins  REACT_17015  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 10165
PRO: PR:Q9UJS0