KCND3 - Potassium voltage-gated channel subfamily D member 3 - human protein (Function)
 
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Protein
Gene
References

 
KCND3 »  Potassium voltage-gated channel subfamily D member 3
 
Protein also known as:  Voltage-gated potassium channel subunit Kv4.3.
Gene name:  KCND3
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 53 2
GENE REF ISO

Function

 show evidences
Overview 
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.  
2
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.2.19  
GO molecular function 
Contributes to A-type (transient outward) potassium channel activitydefinition[GO:0005250]  
1
  • IDABHF-UCL
  • IBARefGenome
Not  Delayed rectifier potassium channel activitydefinition[GO:0005251] silver  
  • IBARefGenome
Ion channel bindingdefinition[GO:0044325]  
1
  • IPIBHF-UCL
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
GO biological process 
Membrane repolarizationdefinition[GO:0086009]  
1
  • IDABHF-UCL
Potassium ion exportdefinition[GO:0071435]  
1
  • IDABHF-UCL
Potassium ion transportdefinition[GO:0006813]  
1
  • TASPINC
Protein homooligomerizationdefinition[GO:0051260] silver  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathway:
Neuronal System  REACT_13685  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KCND3
GenomeRNAi: 3752
PRO: PR:Q9UK17