SLC13A4 - Solute carrier family 13 member 4 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
SLC13A4 »  Solute carrier family 13 member 4
 
Gene name:  SLC13A4
Entry whose protein(s) existence is based on evidence at transcript level
extend overview
1 19 1
GENE REF ISO

Function

 show evidences
Overview 
Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV).  
2
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the divalent anion:na(+) symporter (dass) family  2.A.47.1.14  
GO molecular function 
Sodium:sulfate symporter activitydefinition[GO:0015382]  
1
  • TASPINC
GO biological process 
Sodium ion transmembrane transportdefinition[GO:0035725]  
1
  • TASGOC
Sulfate transportdefinition[GO:0008272]  
1
  • TASPINC
Pathways 
According to Reactome, this protein belongs to the following pathway:
Sodium-coupled sulphate, di- and tri-carboxylate transporters  REACT_20646  
Note 
Transport is inhibited by thiosulfate, phosphate, molybdate, selenate and tungstate. Not inhibited by oxalate, citrate, succinate, phenol red or 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS).  
  • CuratedUniProtKB
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sodium transport  definition   [KW-0739]
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 26266
PRO: PR:Q9UKG4