POU2F3 - POU domain, class 2, transcription factor 3 - human protein (Function)
 
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Protein
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References

 
POU2F3 »  POU domain, class 2, transcription factor 3
 
Protein also known as:  Octamer-binding transcription factor 11 (OTF-11).
Gene name:  POU2F3
Entry whose protein(s) existence is based on evidence at transcript level
extend overview
1 28 3
GENE REF ISO

Function

 show evidences
Overview 
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.  
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Protein dimerization activitydefinition[GO:0046983] silver  
  • IEAOrtholog Compara
RNA polymerase II core promoter proximal region sequence-specific DNA bindingdefinition[GO:0000978]  
1
  • IMPNTNU_SB
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001077]  
2
  • IDANTNU_SB
Sequence-specific DNA bindingdefinition[GO:0043565]  
1
  • IDAMGI
GO biological process 
Epidermis developmentdefinition[GO:0008544]  
1
  • TASPINC
Keratinocyte differentiationdefinition[GO:0030216] silver  
  • IEAOrtholog Compara
Negative regulation by host of viral transcriptiondefinition[GO:0043922]  
1
  • IDAUniProtKB
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944]  
1
  • IDANTNU_SB
Regulation of transcription from RNA polymerase II promoterdefinition[GO:0006357]  
1
  • TASPINC
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
Wound healingdefinition[GO:0042060] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Herpes simplex infection  hsa05168+25833  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: POU2F3
GenomeRNAi: 25833
PRO: PR:Q9UKI9