MYH2 - Myosin-2 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
MYH2 »  Myosin-2
 
Protein also known as:  Myosin heavy chain, skeletal muscle, adult 2.
Gene name:  MYH2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 50 1
GENE REF ISO

Function

 show evidences
Overview 
Muscle contraction. Required for cytoskeleton organization (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Actin bindingdefinition[GO:0003779]  
  • IEAUniProtKB KW
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Calmodulin bindingdefinition[GO:0005516]  
  • IEAUniProtKB KW
Microfilament motor activitydefinition[GO:0000146]  
1
  • TASUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
GO biological process 
Metabolic processdefinition[GO:0008152]  
1
  • TASGOC
Muscle contractiondefinition[GO:0006936]  
2
  • TASUniProtKB
  • IDABHF-UCL
Muscle filament slidingdefinition[GO:0030049]  
1
  • NASBHF-UCL
Plasma membrane repairdefinition[GO:0001778] silver  
  • IEAOrtholog Compara
Response to activitydefinition[GO:0014823] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathways:
Tight junction  hsa04530+4620  
Viral myocarditis  hsa05416+4620  
According to Reactome, this protein belongs to the following pathways:
Immune System  REACT_6900  
Membrane Trafficking  REACT_11123  
Caution 
Represents a conventional myosin. This protein should not be confused with the unconventional myosin-2 (MYO2).  
  • CuratedUniProtKB
 

Keywords

Molecular function 
Motor protein  definition   [KW-0505]
Muscle protein  definition   [KW-0514]
Myosin  definition   [KW-0518]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MYH2
GenomeRNAi: 4620
PRO: PR:Q9UKX2