BARX2 - Homeobox protein BarH-like 2 - human protein (Function)
 
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BARX2 »  Homeobox protein BarH-like 2
 
Gene name:  BARX2
Family name: BAR homeobox
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
  • IEAOrtholog Compara
DNA bindingdefinition[GO:0003677]  
1
  • IDAMGI
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAOrtholog Compara
Transcription regulatory region sequence-specific DNA bindingdefinition[GO:0000976] silver  
  • IEAInterPro 2 GO
GO biological process 
Cartilage condensationdefinition[GO:0001502] silver  
  • IEAOrtholog Compara
Catagendefinition[GO:0042637] silver  
  • IEAOrtholog Compara
Myotube differentiationdefinition[GO:0014902] silver  
  • IEAOrtholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 8538
PRO: PR:Q9UMQ3