DAPP1 - Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
DAPP1 »  Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
 
Gene name:  DAPP1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 49 2
GENE REF ISO

Function

 show evidences
Overview 
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.  
1
  • CuratedUniProtKB
GO molecular function 
Phosphatidylinositol-3,4,5-trisphosphate bindingdefinition[GO:0005547]  
1
  • IDAUniProtKB
Phosphatidylinositol-3,4-bisphosphate bindingdefinition[GO:0043325]  
1
  • IDAUniProtKB
Phospholipid bindingdefinition[GO:0005543]  
1
  • NASUniProtKB
GO biological process 
Protein dephosphorylationdefinition[GO:0006470]  
1
  • NASUniProtKB
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
B cell receptor signaling pathway  hsa04662+27071  
According to Reactome, this protein belongs to the following pathway:
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers  REACT_118700  
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DAPP1
GenomeRNAi: 27071
PRO: PR:Q9UN19