ARHGAP26 - Rho GTPase-activating protein 26 - human protein (Function)
 
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Protein
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ARHGAP26 »  Rho GTPase-activating protein 26
 
Protein also known as:  GTPase regulator associated with focal adhesion kinase.
Gene name:  ARHGAP26
Entry whose protein(s) existence is based on evidence at protein level
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1 32 2
GENE REF ISO

Function

 show evidences
Overview 
GTPase-activating protein for RHOA and CDC42.  
  • CuratedUniProtKB
GO molecular function 
Cytoskeletal adaptor activitydefinition[GO:0008093] silver  
  • IEAInterPro 2 GO
Phospholipid bindingdefinition[GO:0005543]  
1
  • IDAFlyBase
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Rho GTPase activator activitydefinition[GO:0005100]  
1
  • NASUniProtKB
SH3 domain bindingdefinition[GO:0017124] silver  
  • IEAInterPro 2 GO
GO biological process 
Actin cytoskeleton organizationdefinition[GO:0030036]  
1
  • NASUniProtKB
Filopodium assemblydefinition[GO:0046847] silver  
  • IEAInterPro 2 GO
Nervous system developmentdefinition[GO:0007399]  
1
  • NASUniProtKB
Positive regulation of catalytic activitydefinition[GO:0043085]  
1
  • NASGOC
Positive regulation of GTPase activitydefinition[GO:0043547]  
1
  • NASGOC
Positive regulation of Ras GTPase activitydefinition[GO:0032320]  
1
  • NASGOC
Positive regulation of Rho GTPase activitydefinition[GO:0032321]  
1
  • NASGOC
Regulation of catalytic activitydefinition[GO:0050790]  
1
  • NASGOC
Pathways 
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
GTPase activation  definition   [KW-0343]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ARHGAP26
GenomeRNAi: 23092
PRO: PR:Q9UNA1