A4GNT - Alpha-1,4-N-acetylglucosaminyltransferase - human protein (Function)
 
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Protein
Gene
References

 
A4GNT »  Alpha-1,4-N-acetylglucosaminyltransferase   [ EC 2.4.1.- ]  (Alpha4GnT)
 
Gene name:  A4GNT
Family name: Glycosyltransferase 32
Entry whose protein(s) existence is based on evidence at transcript level
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1 11 1
GENE REF ISO

Function

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Overview 
Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans.  
  • CuratedUniProtKB
GO molecular function 
Acetylglucosaminyltransferase activitydefinition[GO:0008375]  
1
  • IDAMGI
Galactosyltransferase activitydefinition[GO:0008378] silver  
  • IEAInterPro 2 GO
GO biological process 
Carbohydrate metabolic processdefinition[GO:0005975]  
1
  • TASPINC
Glycoprotein biosynthetic processdefinition[GO:0009101]  
1
  • IDAMGI
Negative regulation of epithelial cell proliferationdefinition[GO:0050680] silver  
  • IEAOrtholog Compara
Protein O-linked glycosylationdefinition[GO:0006493] silver  
  • IEAOrtholog Compara
Enzymatic activity 
According to CAZy, this protein is belongs to the following pathway:
Glycosyltransferase Family 32  GT32  
Pathways 
This protein is involved in the following pathway
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 51146
PRO: PR:Q9UNA3