LHX6 - LIM/homeobox protein Lhx6 - human protein (Function)
 
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LHX6 »  LIM/homeobox protein Lhx6  (LIM homeobox protein 6)
 
Protein also known as:  LIM/homeobox protein Lhx6.1.
Gene name:  LHX6
Entry whose protein(s) existence is based on evidence at protein level
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1 23 6
GENE REF ISO

Function

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Overview 
Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity).  
1
  • UniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
1
  • InterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
1
  • UniProtKB
Zinc ion bindingdefinition[GO:0008270] silver  
1
  • InterPro 2 GO
GO biological process 
Cell maturationdefinition[GO:0048469]  
1
  • Ortholog Curator
Cerebral cortex GABAergic interneuron migrationdefinition[GO:0021853]  
1
  • Ortholog Curator
Cerebral cortex radially oriented cell migrationdefinition[GO:0021799]  
1
  • Ortholog Curator
Cerebral cortex tangential migrationdefinition[GO:0021800]  
1
  • Ortholog Curator
Forebrain neuron fate commitmentdefinition[GO:0021877] silver  
1
  • Ortholog Compara
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
1
  • UniProtKB KW
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Neurogenesis  definition   [KW-0524]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: LHX6
GenomeRNAi: 26468
PRO: PR:Q9UPM6