ICK - Serine/threonine-protein kinase ICK - human protein (Function)
 
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ICK »  Serine/threonine-protein kinase ICK   [ EC 2.7.11.22 ]
 
Protein also known as:  Laryngeal cancer kinase 2 (LCK2).
Gene name:  ICK
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 33 2
GENE REF ISO

Function

 show evidences
Overview 
May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity).  
2
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • IDAUniProtKB
Cyclin-dependent protein serine/threonine kinase activitydefinition[GO:0004693]  
  • IEAEC 2 GO
Magnesium ion bindingdefinition[GO:0000287]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
Protein serine/threonine kinase activitydefinition[GO:0004674]  
1
  • IDAUniProtKB
GO biological process 
Intracellular signal transductiondefinition[GO:0035556]  
1
  • IDAUniProtKB
Multicellular organismal developmentdefinition[GO:0007275]  
  • IEAUniProtKB KW
Protein phosphorylationdefinition[GO:0006468]  
1
  • IDAUniProtKB
Signal transductiondefinition[GO:0007165]  
1
  • TASUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.22: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
It requires the following cofactor
Magnesium.  
1
  • CuratedUniProtKB
 

Keywords

Molecular function 
Developmental protein  definition   [KW-0217]
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: ICK_(gene)
GenomeRNAi: 22858
PRO: PR:Q9UPZ9
Chemistry
GuidetoPHARMACOLOGY: 2038