FARSA - Phenylalanine--tRNA ligase alpha subunit - human protein (Function)
 
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Protein
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References

 
FARSA »  Phenylalanine--tRNA ligase alpha subunit   [ EC 6.1.1.20 ]
 
Protein also known as:  Phenylalanyl-tRNA synthetase alpha subunit (PheRS).
Gene name:  FARSA
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

 show evidences
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Phenylalanine-tRNA ligase activitydefinition[GO:0004826]  
  • IEAEC 2 GO
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
tRNA bindingdefinition[GO:0000049] silver  
  • IEAInterPro 2 GO
GO biological process 
Phenylalanyl-tRNA aminoacylationdefinition[GO:0006432] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 6.1.1.20: ATP + L-phenylalanine + tRNA(Phe) AMP + diphosphate + L-phenylalanyl-tRNA(Phe).  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathway:
Aminoacyl-tRNA biosynthesis  hsa00970+2193  
According to Reactome, this protein belongs to the following pathway:
Gene Expression  REACT_71  
 

Keywords

Biological process 
Protein biosynthesis  definition   [KW-0648]
Molecular function 
Aminoacyl-tRNA synthetase  definition   [KW-0030]
Ligase  definition   [KW-0436]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FARSA_(gene)
GenomeRNAi: 2193
PRO: PR:Q9Y285