B3GNT3 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 - human protein (Function)
 
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B3GNT3 »  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3   [ EC 2.4.1.146 ]  (BGnT-3)
 
Protein also known as:  UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8.
Gene name:  B3GNT3
Family name: Glycosyltransferase 31
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides.  
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  • CuratedUniProtKB
GO molecular function 
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activitydefinition[GO:0047223]  
  • IEAEC 2 GO
Galactosyltransferase activitydefinition[GO:0008378] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.4.1.146: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-(N-acetyl-D-glucosaminyl-(1->6))-N-acetyl-D-galactosaminyl-R UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-(N-acetyl-D-glucosaminyl-(1->6))-N-acetyl-D-galactosaminyl-R.  
1
  • CuratedUniProtKB
According to CAZy, this protein is belongs to the following pathway:
Glycosyltransferase Family 31  GT31  
 
More information is available from:
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycosphingolipid biosynthesis - lacto and neolacto series  hsa00601+10331  
Metabolic pathways  hsa01100+10331  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Metabolism  REACT_111217  
Metabolism of proteins  REACT_17015  
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links