EPB41L3 - Band 4.1-like protein 3 - human protein (Function)
 
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EPB41L3 »  Band 4.1-like protein 3
 
Protein also known as:  Differentially expressed in adenocarcinoma of the lung protein 1 (DAL-1). Cleaved into:  Band 4.1-like protein 3, N-terminally processed.
Gene name:  EPB41L3
Entry whose protein(s) existence is based on evidence at protein level
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1 76 4
GENE REF ISO

Function

 show evidences
Overview 
Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.  
4
  • CuratedUniProtKB
GO molecular function 
Actin bindingdefinition[GO:0003779]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Structural constituent of cytoskeletondefinition[GO:0005200]  
1
  • TASBHF-UCL
GO biological process 
Apoptotic processdefinition[GO:0006915]  
  • IEAUniProtKB KW
Cortical actin cytoskeleton organizationdefinition[GO:0030866] silver  
  • IEAInterPro 2 GO
Cortical cytoskeleton organizationdefinition[GO:0030865]  
1
  • TASBHF-UCL
Cytoskeletal anchoring at plasma membranedefinition[GO:0007016]  
1
  • TASBHF-UCL
Myelin maintenancedefinition[GO:0043217]  
  • ISSOrtholog Curator
Neuron projection morphogenesisdefinition[GO:0048812]  
  • ISSOrtholog Curator
Paranodal junction assemblydefinition[GO:0030913]  
  • ISSOrtholog Curator
Protein localization to juxtaparanode region of axondefinition[GO:0071205]  
  • ISSOrtholog Curator
Protein localization to paranode region of axondefinition[GO:0002175]  
  • ISSOrtholog Curator
Protein localization to plasma membranedefinition[GO:0072659]  
  • ISSOrtholog Curator
Regulation of cell shapedefinition[GO:0008360]  
  • ISSOrtholog Curator
Pathways 
According to KEGG, this protein belongs to the following pathway:
Tight junction  hsa04530+23136  
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: EPB41L3
GenomeRNAi: 23136
PRO: PR:Q9Y2J2