LSM2 - U6 snRNA-associated Sm-like protein LSm2 - human protein (Function)
 
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Protein
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LSM2 »  U6 snRNA-associated Sm-like protein LSm2
 
Protein also known as:  Small nuclear ribonuclear protein D homolog.
Gene name:  LSM2
Family name: snRNP Sm proteins
Entry whose protein(s) existence is based on evidence at protein level
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1 25 1
GENE REF ISO

Function

 show evidences
Overview 
Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.  
  • CuratedUniProtKB
GO molecular function 
Poly(A) RNA bindingdefinition[GO:0044822]  
2
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
6
  • IPIIntAct
Protein kinase bindingdefinition[GO:0019901] silver  
  • IEAOrtholog Compara
U6 snRNA bindingdefinition[GO:0017070]  
1
  • NASUniProtKB
GO biological process 
mRNA splicing, via spliceosomedefinition[GO:0000398]  
1
  • ICUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
RNA degradation  hsa03018+57819  
Spliceosome  hsa03040+57819  
According to Reactome, this protein belongs to the following pathways:
mRNA decay by 5' to 3' exoribonuclease  REACT_20518  
mRNA Splicing - Major Pathway  REACT_467  
mRNA Splicing - Minor Pathway  REACT_1753  
 

Keywords

Biological process 
mRNA processing  definition   [KW-0507]
mRNA splicing  definition   [KW-0508]
Molecular function 
Ribonucleoprotein  definition   [KW-0687]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: LSM2
GenomeRNAi: 57819
PRO: PR:Q9Y333