ADAM18 - Disintegrin and metalloproteinase domain-containing protein 18 - human protein (Function)
 
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ADAM18 »  Disintegrin and metalloproteinase domain-containing protein 18  (ADAM 18)
 
Protein also known as:  Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III (tMDC III).
Gene name:  ADAM18
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Metalloendopeptidase activitydefinition[GO:0004222] silver  
  • IEAInterPro 2 GO
Metallopeptidase activitydefinition[GO:0008237]  
1
  • TASPINC
Zinc ion bindingdefinition[GO:0008270] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell differentiationdefinition[GO:0030154]  
  • IEAUniProtKB KW
Multicellular organismal developmentdefinition[GO:0007275]  
  • IEAUniProtKB KW
Proteolysisdefinition[GO:0006508] silver  
  • IEAInterPro 2 GO
Spermatogenesisdefinition[GO:0007283]  
  • IEAUniProtKB KW
Enzymatic activity 
 
More information is available from:
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Spermatogenesis  definition   [KW-0744]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ADAM18
GenomeRNAi: 8749
PRO: PR:Q9Y3Q7