PPIAL4A » Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C (PPIase A-like 4A)

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Protein also known as: Cyclophilin homolog overexpressed in liver cancer.

Gene name: PPIAL4A ; PPIAL4B ; PPIAL4C

Family name: Cyclophilin-type PPIase » PPIase A

This protein has been shown to exist at protein level

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3 43 1

GENE REF ISO

Function

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Overview

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

CuratedUniProtKB

GO molecular function

Peptidyl-prolyl cis-trans isomerase activitydefinition[GO:0003755]

IEAEC 2 GO

GO biological process

Protein foldingdefinition[GO:0006457]

IEAUniProtKB KW

Enzymatic activity

This protein acts as an enzyme. It is known to catalyze the following reaction

EC 5.2.1.8: Peptidylproline (omega⇄180) ⇄ peptidylproline (omega⇄0).

CuratedUniProtKB

Note

It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 1.

CuratedUniProtKB

Keywords

Molecular function

Isomerase definition [KW-0413]

Rotamase definition [KW-0697]

Technical term

Reference proteome definition [KW-1185]

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Function

Keywords

neXtProt