GTF3C5 - General transcription factor 3C polypeptide 5 - human protein (Function)
 
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GTF3C5 »  General transcription factor 3C polypeptide 5
 
Protein also known as:  Transcription factor IIIC subunit epsilon.
Gene name:  GTF3C5
Family name: TFIIIC subunit 5
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 23 3
GENE REF ISO

Function

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Overview 
Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.  
  • CuratedUniProtKB
GO molecular function 
Contributes to DNA bindingdefinition[GO:0003677]  
1
  • ICHGNC
Protein bindingdefinition[GO:0005515]  
1
  • IPIHGNC
GO biological process 
5S class rRNA transcription from RNA polymerase III type 1 promoterdefinition[GO:0042791]  
1
  • ICHGNC
Skeletal muscle cell differentiationdefinition[GO:0035914] silver  
  • IEAOrtholog Compara
Transcription from RNA polymerase III promoterdefinition[GO:0006383]  
1
  • ICHGNC
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • ICHGNC
tRNA transcription from RNA polymerase III promoterdefinition[GO:0042797]  
1
  • ICHGNC
Pathways 
According to Reactome, this protein belongs to the following pathways:
RNA Polymerase III Abortive And Retractive Initiation  REACT_22339  
RNA Polymerase III Transcription Initiation From Type 1 Promoter  REACT_347  
RNA Polymerase III Transcription Initiation From Type 2 Promoter  REACT_1036  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GTF3C5
GenomeRNAi: 9328
PRO: PR:Q9Y5Q8