CYP46A1 - Cholesterol 24-hydroxylase - human protein (Sequence)
 
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Protein
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CYP46A1 »  Cholesterol 24-hydroxylase   [ EC 1.14.13.98 ]  (CH24H)
 
Protein also known as:  Cytochrome P450 46A1.
Gene name:  CYP46A1
Family name: Cytochrome P450
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 45 3
GENE REF ISO

Displayed isoform: Iso 1     

 
 
Isoform Iso 1   500 aaMass: 56821 Da,  pI: 9.15
MSPGLLLLGS AVLLAFGLCC TFVHRARSRY EHIPGPPRPS FLLGHLPCFW KKDEVGGRVL QDVFLDWAKK YGPVVRVNVF HKTSVIVTSP ESVKKFLMST KYNKDSKMYR ALQTVFGERL FGQGLVSECN YERWHKQRRV IDLAFSRSSL VSLMETFNEK AEQLVEILEA KADGQTPVSM QDMLTYTAMD ILAKAAFGME TSMLLGAQKP LSQAVKLMLE GITASRNTLA KFLPGKRKQL REVRESIRFL RQVGRDWVQR RREALKRGEE VPADILTQIL KAEEGAQDDE GLLDNFVTFF IAGHETSANH LAFTVMELSR QPEIVARLQA EVDEVIGSKR YLDFEDLGRL QYLSQVLKES LRLYPPAWGT FRLLEEETLI DGVRVPGNTP LLFSTYVMGR MDTYFEDPLT FNPDRFGPGA PKPRFTYFPF SLGHRSCIGQ QFAQMEVKVV MAKLLQRLEF RLVPGQRFGL QEQATLKPLD PVLCTLRPRG WQPAPPPPPC

Keywords

Coding sequence diversity 
Alternative splicing  definition   [KW-0025]
Domain 
Transmembrane  definition   [KW-0812]
Transmembrane helix  definition   [KW-1133]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
Gene3D: 1.10.630.10
InterPro: IPR002401 [ Cyt P450 E grp-I ]
InterPro: IPR001128 [ Cyt P450 ]
InterPro: IPR017972 [ Cyt P450 CS ]
Pfam: PF00067 [ p450 ]
PRINTS: PR00385 [ P450 ]
PRINTS: PR00463 [ EP450I ]
PROSITE: PS00086 [ CYTOCHROME P450 ]
SUPFAM: SSF48264 [ SSF48264 ]
Genome annotation databases
Ensembl: Transcript: ENST00000261835;  Protein: ENSP00000261835;  Gene: ENSG00000036530.
Ensembl: Transcript: ENST00000423126;  Protein: ENSP00000405779;  Gene: ENSG00000036530.
Ensembl: Transcript: ENST00000554611;  Protein: ENSP00000451069;  Gene: ENSG00000036530.
Ensembl: Transcript: ENST00000380228;  Protein: ENSP00000369577;  Gene: ENSG00000036530.
Ensembl: Transcript: ENST00000554176;  Protein: ENSP00000450553;  Gene: ENSG00000036530.
Ensembl: Transcript: ENST00000554917;  Protein: ENSP00000452151;  Gene: ENSG00000036530.
Ensembl: Transcript: ENST00000556313;  Protein: ENSP00000451602;  Gene: ENSG00000036530.
KEGG: hsa:10858
UCSC: uc001ygo.3
Organism-specific databases
MGI: MGI:1341877 [ Cyp46a1 ]
Other
ChiTaRS: CYP46A1
EvolutionaryTrace: Q9Y6A2
PTM databases
PhosphoSite: Q9Y6A2
Phylogenomic databases
eggNOG: COG2124
HOGENOM: HOG000290190
HOVERGEN: HBG102502
InParanoid: Q9Y6A2
KO: K07440
OMA: RPRGWQP
PhylomeDB: Q9Y6A2
Sequence databases
CCDS: CCDS9954.1 [ Q9Y6A2-1 ]
EMBL: Genomic DNA:  AL160313 . No translation available.
EMBL: mRNA:  AK295216 . Translation:  BAG58210.1 .
EMBL: Genomic DNA:  AL136000 . No translation available.
EMBL: mRNA:  AK090886 . Translation:  BAC03539.1 .
EMBL: mRNA:  BC022539 . Translation:  AAH22539.1 .
EMBL: mRNA:  AF094480 . Translation:  AAD41244.1 .
IPI: IPI00002133
RefSeq: Protein:  NP_006659.1. Nucleotide sequence:  NM_006668.1.
UniProtKB: Q9Y6A2