USH1C - Harmonin - human protein (Function)
 
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Protein
Gene
References

 
USH1C »  Harmonin
 
Protein also known as:  Autoimmune enteropathy-related antigen AIE-75.
Gene name:  USH1C
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 52 5
GENE REF ISO

Function

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Overview 
Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity).  
1
  • UniProtKB
GO molecular function 
Myosin tail bindingdefinition[GO:0032029] silver  
1
  • Ortholog Compara
Protein bindingdefinition[GO:0005515]  
3
  • IntAct
  • HGNC
Spectrin bindingdefinition[GO:0030507]  
1
  • MGI
GO biological process 
Auditory receptor cell differentiationdefinition[GO:0042491] silver  
1
  • Ortholog Compara
Equilibrioceptiondefinition[GO:0050957]  
1
  • HGNC
G2/M transition of mitotic cell cycledefinition[GO:0000086]  
1
  • HGNC
Inner ear morphogenesisdefinition[GO:0042472] silver  
1
  • Ortholog Compara
Parallel actin filament bundle assemblydefinition[GO:0030046] silver  
1
  • Ortholog Compara
Photoreceptor cell maintenancedefinition[GO:0045494]  
1
  • HGNC
Sensory perception of light stimulusdefinition[GO:0050953]  
1
  • HGNC
Sensory perception of sounddefinition[GO:0007605]  
1
  • HGNC
 

Keywords

Biological process 
Hearing  definition   [KW-1009]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: USH1C
GenomeRNAi: 10083
PRO: PR:Q9Y6N9