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Terminology View
Terminology
 
GO:0004222 » Metalloendopeptidase activity
Ontology
Gene Ontology molecular function »  GO:0004222
Definition
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Synonyms
  • Metalloendoprotease activity
  • Metalloendoproteinase activity
There are 103 proteins involved in this biological function in the human proteome.
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